Category: drug interaction

Spironolactone and Photosensitivity

A patient asked me if spironolactone caused photosensitivity. After careful research on the subject, I found that photosensitivity was not a side effect of spironolactone specifically. But it can be caused by hydrochlorothiazide, which the other chemical ingredient in Aldactazide® tablets. The short answer is not directly. But if the patient is taking Aldactazide® tablets, photosensitivity could be a side effect.

REFERENCES:

Aldactazide® spironolactone and hydrochlorothiazide tablets . www.accessdata.fda.gov. http://www.accessdata.fda.gov/drugsatfda_docs/label/2014/012616s074lbl.pdf. Published January 14, 2016. Accessed June 29, 2016.

Vomiting: Side Effect of Imiquimod

A few weeks ago, a patient called me, questioning whether IMIQUIMOD was associated with vomiting. The patient had been applying IMIQUIMOD once a week to their facial skin for maintenance therapy of ACTINIC KERATOSES. At first, I thought, “How could this be? How could a topical medication make someone nauseous and vomit?” After researching this question, I found out that it is true: approximately 1% of patients in clinical trials develop vomiting. This, I suppose, is from the generation of interferon.